Most of chemotherapy patients are old with a long course and a heavy condition. The patient's vascular conditions are poor, and many anti-tumor drugs are irritating to blood vessels, which can cause embolic phlebitis. If the drug is infiltrated into subcutaneous tissue, it can cause redness, pain, inflammation, and even tissue necrosis and ulceration. In order to alleviate the suffering of patients, our hospital has developed deep vein catheterization technology more than 10 years ago and accumulated plenty of experience in catheterization and nursing. Short-term percutaneous central venous catheterization (CVC) provides a guarantee for the smooth operation of a large number of transfusion, infusion and rescue medications for critically ill patients because of its large lumen, rapid blood flow and fixed position, and also becomes one of the most important measures of venous access to supply nutritional support for chronic disease patients. Peripherally inserted central catheter (PICC) has a high primary success rate catheterization, which is safe, and saves time and manpower. PICC has been widely used in clinical patients since there is no need for local anesthesia or stitching, and there is no restriction on patient's arm activity.